CK‐18 cell death markers improve the prediction of histological remission in autoimmune hepatitis during biochemical remission
نویسندگان
چکیده
منابع مشابه
Cyclosporine induced biochemical remission in childhood autoimmune hepatitis.
The conventional treatment of autoimmune hepatitis (AIH) in children, which includes prednisone alone or in combination with azathioprine, induces remission in most cases but is often associated with poorly tolerated side effects. To avoid the adverse effects, Alvarez et al. introduced an alternative treatment regimen, using cyclosporine A (CyA) as primary immunosuppression. We carried out a re...
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The standard therapy for some autoimmune diseases consists of a combination of corticosteroids and thiopurines. In non-responders to thiopurine drugs, the measurement of the metabolites of azathioprine, 6-thioguanine, and 6-methylmercaptopurine, can be a useful tool. The measurement has been used during the treatment of inflammatory bowel diseases and, less commonly, in autoimmune hepatitis. Ma...
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Concurrence of nonalcoholic steatohepatitis (NASH) with autoimmune hepatitis (AIH) is a rare condition that is challenging to diagnosis, due to the relatively high prevalence of autoantibodies in NASH. It is also difficult to determine the most effective treatment as corticosteroids are likely to worsen NASH despite being effective in the treatment of AIH. In this case report, we present a fema...
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aim : in the current study, we aimed at identifying independent laboratory parameter to predict liver damage. background : although liver biopsy is frequently recommended in assessing disease severity and selecting antiviral treatment candidates, it has several limitations. patients and methods : a total of 527 patients with untreated chronic hepatitis b virus infection were selected. a percuta...
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Many papers have discussed the advisability of administering intensive chemotherapy to older patients with untreated acute myeloid leukemia (AML). More specifically, several studies have attempted to identify patients at particularly high risk of induction death following such therapy. However, the issue of chemotherapy-induced death once patients are in complete remission (CR) has received les...
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ژورنال
عنوان ژورنال: Liver International
سال: 2020
ISSN: 1478-3223,1478-3231
DOI: 10.1111/liv.14699